Suppression
Resveratrol
Category: Natural chemicals
Type
Voluntary
Introduction and description
description shortly
Dr Duke’s list of activity for RESVERATROL
Activity |
*Reference |
5-HETE-Inhibitor IC50=3-9 uM |
* |
5-HT-Inhibitor IC50=3-9 uM |
* |
5-Lipoxygenase-Inhibitor IC50=1-9 uM |
* |
5-Lipoxygenase-Inhibitor IC50=48 uM |
* |
Akt-Inhibitor |
* |
Antiaggregant IC50=0.016-232 uM/L |
* |
Antiaggregant IC50=100 uM |
* |
Antiangiogenic |
* |
Antibacterial |
* |
Anticancer |
* |
Anticarcinogenic |
* |
Antiedemic ED50 |
* |
Antieicosanoid |
* |
Antiinflammatory IC50=2.6 uM |
* |
Antileukemic 15-30 uM |
* |
Antileukotriene IC50=1.37 uM |
* |
Antilipoperoxidant IC50=2 mg/L |
* |
Antimutagenic ED50=4 uM |
* |
Antioxidant IC50=2 mg/L |
* |
Antioxidant 2 x Vit. E |
* |
Antiperoxidant |
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. |
Antiproliferant |
* |
Antiprostaglandin IC50=2.6 uM |
* |
Antiradicular ED50=27 uM |
* |
Antiseptic |
* |
Antithrombic IC50=100 uM |
* |
Antitumor |
* |
Antitumor (Mammary) ED50=3.1 uM |
* |
Antitumor (Prostate) 25 uM |
* |
Antitumor (Skin) ID68=1 uM |
* |
Antitumor (Skin) 5+ uM |
* |
Apoptotic IC50=15-30 uM |
* |
Artemicide |
* |
Beta-Glucuronidase-Inhibitor IC50=~25 uM |
* |
Cardioprotective |
* |
Casein-Kinase-II-Inhibitor |
* |
Chemopreventive |
* |
COX-1-Inhibitor ED50=15 uM |
* |
COX-1-Inhibitor 50 uM/ |
Jang, M. S., Pezzuto, J. M. 1998. Resveratrol Blocks Eicosanoid Production and Chemically-Induced Cellular Transformation: Implication for Cancer Chemoprevention. Pharm Biol Suppl, 36: 28-34. |
COX-2-Inhibitor 50 uM/ |
* |
COX-2-Inhibitor >2.5->22.5 uM |
* |
COX-2-Inhibitor 50 uM/ |
* |
Cyclooxygenase-Inhibitor IC50=15 uM |
* |
CYP1A1-Inhibitor |
* |
Differentiator IC50=18 uM |
* |
Elastase-Inhibitor IC50=37 uM |
* |
Estrogenic 22% of genistein |
* |
Fungicide |
Chemical Constituents of Oriental Herbs (3 diff. books) |
Hepatoprotective |
* |
HIF-1alpha-Inhibitor |
* |
Hydroperoxidase-Inhibitor |
* |
Hypocholesterolemic |
* |
Hypotriglyceridemic |
Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. |
IKB-kinase-Inhibitor |
* |
JNK-Inhibitor |
* |
Lipolytic |
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. |
MAPK-Inhibitor |
* |
NADH-Ubiquinone-Oxidoreductase-Inhibitor |
* |
NF-kB-Inhibitor |
* |
Ornithine-Decarboxylase-Inhibitor |
* |
Pesticide |
* |
Phytoalexin |
* |
PKC-Inhibitor |
* |
PKD-Inhibitor |
* |
PTK-Inhibitor 110-263 uM |
* |
Quinone-Reductase-Inducer ED100=21 uM |
* |
Topoisomerase-II-Inhibitor IC50=49 uM |
Sun, N. J., Woo, S. H., Cassady, J. M., Snapka, R. M. 1998. DNA Polymerase and Topoisomerase II Inhibitors From Psoralea corylifolia. J Natural Products, 61: 362-366. |
VEGF-Inhibitor |
* |
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
Related observations
Healing observations
- Cancer and various foods 006256
- Dr Duke's list of Chemicals and their Biological Activities in: Morus alba L. (Moraceae) -- Sang-Pai-Pi, White Mulberry 027433
- Dr Duke's list of Plants containing RESVERATROL 023253
- Effects of dietary polyphenols on metabolic syndrome features in humans: a systematic review 021219
- Resveratrol is cidal to both classes of Haemophilus ducreyi 023252