Overload
Migraine treatments
Category: Medicines
Type
Involuntary
Introduction and description
According to the eHealthme web site over 120 drugs are prescribed for migraine, a list of them can be found by following this LINK.
Amongst this list are drugs that are found elsewhere on this website and intended for use with other illnesses, for example:
- Aspirin and NSAIDs, paracetemol and drugs like Baclofen, Excedrin
- Tricyclic antidepressants [TCAs] like Amitryptaline/Elavil, Nortryptaline
- Opioid based analgesics like Butorphanol and Dilaudid
- Beta blockers like Nebivolol and Atenolol
- Calcium channel blockers like Verapramil
- Depression and anti-anxiety treatments like Cimbalta/Duloxetine
- Epilepsy drugs – like Depakote and Valproate, Gabapentin, Topamax
- Anti-depressant SSRIs like Effexor and Serzone [see observation below]
- Barbiturates like Fioricet
- Anti-emetics like Reglan [see the observation below]
If you look at the description for migraine you should be able to see that none of these actually address the causes of migraine. The only class of drug that exists with the specific aim of treating migraines are called Triptans and Triptans have caused hallucinations.
Background
Triptans are a family of tryptamine-based drugs used specifically in the treatment of migraines and cluster headaches. They were first introduced in the 1990s.
“While effective at treating individual headaches, they do not provide preventative treatment and are not considered a cure”.
Their action is “attributed to their agonist effects on serotonin 5-HT1B and 5-HT1D receptors in cranial blood vessels causing their constriction”. So in effect they are vasoconstrictors and prevent blood from getting to the brain. Since some migraine attacks result in over dilation of blood vessels in the brain, then the somewhat simplistic theory is that any medication that constricts the vessels will relieve the pressure. As you should be able to see, however, the potential for things going wrong is very high, as the cause may not be over dilation it may be toxins, viruses, mineral deficiency and imbalance, vitamin deficiency or imbalance or other problems.
As such if you use these drugs the overall effect will be hypoxia which is why there are hallucinations. If you have a poorly heart, it may be a lot worse as is shown by the side effects of many of these drugs which list heart attacks, palpitations and cardiac arrest.
Side effects
Many of these drugs work via serotonin and its ability to produce vasoconstriction.
Unfortunately serotonin has other functions and the disruption to these functions is apparent in the sorts of side effects experienced.
If we take an example drug such as Amerge, then the side effects as stated on eHealthme and derived from ADRs are as follows:
Most common side effects by gender :
Female | Male |
Drug Ineffective | Drug Ineffective |
Nausea | Nausea |
Chest Pain | Vomiting |
Fatigue | Petechiae |
Headache | Anxiety |
Pain | Confusional State |
Migraine | Insomnia |
Depression | Headache |
Arthralgia | Asthenia |
Anxiety | Pyrexia |
Pyrexia is another word for fever. Arthralgia is joint pain. Compare the results with another drug, Maxalt, and you will be able to see that the side-effects are not dissimilar. All these symptoms are indicators of serotonin imbalance.
Most common side effects by gender :
Female | Male |
Nausea | Drug Ineffective |
Headache | Headache |
Pain | Migraine |
Migraine | Chest Pain |
Anxiety | Myocardial Infarction |
Vomiting | Depression |
Chest Pain | Nausea |
Fatigue | Anxiety |
Dizziness | Fatigue |
Drug Ineffective | Dyspnoea |
Dyspnoea is shortness of breath, often experienced when the heart is in trouble.
Deaths
If we now look at the ultimate spiritual experience - death - then we also see that these drugs have caused deaths. The deaths again seemed to be attributable to the vasoconstriction, which appears to be acting somewhat indiscriminately
Amerge - On Aug, 9, 2015: 713 people reported to have side effects when taking Amerge. Among them, 4 people (0.56%) have Death
Axert - On Jul, 22, 2015: 414 people reported to have side effects when taking Axert. Among them, 8 people (1.93%) have Death
Maxalt - On Jul, 11, 2015: 3,614 people reported to have side effects when taking Maxalt. Among them, 31 people (0.86%) have Death
Relpax - On Jul, 18, 2015: 2,842 people reported to have side effects when taking Relpax. Among them, 13 people (0.46%) have Death
Sumatripan - On Jul, 25, 2015: 3,340 people reported to have side effects when taking Sumatriptan. Among them, 26 people (0.78%) have Death
Imitrex - On Aug, 5, 2015: 5,201 people reported to have side effects when taking Imitrex. Among them, 29 people (0.56%) have Death
Treximet - On Jul, 20, 2015: 879 people reported to have side effects when taking Treximet. Among them, 4 people (0.46%) have Death
Zomig - On Aug, 9, 2015: 3,675 people reported to have side effects when taking Zomig. Among them, 15 people (0.41%) have Death
Eletriptan- On Aug, 9, 2015: 48 people reported to have side effects when taking Eletriptan hydrobromide. Among them, 1 people (2.08%) has Death
Rizatriptan - On Aug, 9, 2015: 237 people reported to have side effects when taking Rizatriptan benzoate. Among them, 3 people (1.27%) have Death
How it works
References and further reading
All photos by Carla MascaroObservations
The table below shows the number of hallucinations as reported on the eHealthme web site as at October 2013, for up to date numbers see this site. The link takes you to the side effects for these drugs on the eHealthme site.
In those cases where no hallucinations have been recorded, it does not mean the drug has not produced any, only that the drug is not sold in the USA under that name
Medicine |
Total number of hallucinations |
11 |
|
Almotriptan |
0 |
Naramig |
0 |
Naratriptan |
0 |
1 |
|
Almogran |
0 |
Almotrex |
0 |
Amignul |
0 |
Avitriptan (BMS-180,048) |
0 |
Frovatriptan |
0 |
2 |
|
Migard |
0 |
Frovamig |
0 |
16 |
|
Eletriptan |
0 |
Rizatriptan |
0 |
7 |
|
14 |
|
20 |
|
Imigran |
0 |
Cinie |
0 |
Illument |
0 |
Migriptan |
0 |
6 |
|
2 |
|
13 |
|
TOTAL |
92 |
Related observations
Healing observations
- Cure for Migraine MDMA (Ecstasy) by Respondent 70 020285
- Dr Duke’s list of the top 40 plants with Antimigraine activity 021412
- Energy Metabolism Impairment in Migraine 027374
- Feverfew - The Healing power of herbs – Ceres Esplan 019998
- Mindfulness and headache: A 'new' old treatment, with new findings 023458
- Polizzi, Nick - Curing migraine 020237
Hallucination
- Acute psychotic symptoms induced by topiramate 029489
- Amerge 017353
- Amitril 017993
- Amitriptyline hydrochloride 015646
- Axert 017354
- Blocadren 018049
- Botox 018051
- Cabergoline 017431
- Cafergot 023547
- Chronic analgesic induced headaches 012215
- Clonidine 005096
- Clopra 018215
- Compazine 017343
- Divalproex and Divalproex sodium 024028
- Dr Penny Sartori - Hallucinations are usually caused by pharmaceuticals in hospitals 014533
- Eletriptan hydrobromide 018939
- Epival 024029
- Esgic 018963
- Fairy lights patterns and circles 014434
- Frova 019078
- Frova and Frovatriptan 017355
- Maxalt 005746
- Maxolon or Metaclopramide 017335
- Methergine 019520
- Metoclopramide 019525
- Migraine, headache and pain killers 005751
- Migraines and ergotism 006802
- Nadolol 019667
- Pramipexole 015662
- Prochlorperazine, Edisylate and Maleate 019865
- Reglan 015692
- Relpax and Relert 017356
- Serzone 005494
- Sumatriptan and Imitrex 017357
- Sumatriptan Succinate 020056
- Taztia Xt 020183
- The Netherlands Centre for Monitoring of Adverse Reactions to Drugs 1992 016811
- Timoptic & Timoptic-xe 020210
- Tizanidine 016875
- Toprol 015755
- Treximet and POZEN 017358
- Zanaflex 016874
- Zolmitriptan and Zomig 017359
- Zomig-zmt 020471