Observations placeholder
Cabergoline
Identifier
017431
Type of Spiritual Experience
Background
A description of the experience
Cabergoline (brand names Caberlin, Dostinex and Cabaser), an ergot derivative. Although cabergoline is commonly described principally as a dopamine D2 receptor agonist, it also possesses significant affinity for the D3, D4, 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, α2B- receptors, and moderate/low affinity for the D1 and 5-HT7 receptors. Cabergoline functions as an agonist at all of these receptors except for 5-HT7 and α2B-, where it acts as an antagonist.
It is frequently used as a first-line agent in the management of prolactinomas. A prolactinoma is a benign tumor (adenoma) of the pituitary gland that produces a hormone called prolactin.
Prolactin stimulates the breast to produce milk, and has many other functions such as regulation of mood. Hence prolactin levels are usually higher during pregnancy and after childbirth. In males it is responsible for the sexual refractory period after orgasm and excess levels can lead to erectile dysfunction.
It has been used off label as an adjunct to SSRI antidepressants to counteract the side effects of those drugs, such as reduced libido and anorgasmia. It also has been used off label by men to reduce or eliminate the male refractory period, thereby allowing men to experience multiple ejaculatory orgasms in rapid succession.
There has been some off-line use as a migraine and cluster headache treatment due to its serotonin action
On Aug, 2, 2015: 2,265 people reported to have side effects when taking Cabergoline. Among them, 120 people (5.30%) have Hallucination.
Time on Cabergoline when people have Hallucination :
< 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
Hallucination | 29.31% | 17.24% | 15.52% | 18.97% | 10.34% | 8.62% | 0.00% |
Age of people who have Hallucination when taking Cabergoline :
0-1 | 2-9 | 10-19 | 20-29 | 30-39 | 40-49 | 50-59 | 60+ | |
Hallucination | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 3.03% | 12.12% | 84.85% |
On Aug, 1, 2015: 2,265 people reported to have side effects when taking Cabergoline. Among them, 18 people (0.79%) have Death.
Time on Cabergoline when people have Death :
< 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
Death | 40.00% | 20.00% | 0.00% | 0.00% | 0.00% | 40.00% | 0.00% |
Age of people who have Death when taking Cabergoline :
0-1 | 2-9 | 10-19 | 20-29 | 30-39 | 40-49 | 50-59 | 60+ | |
Death | 0.00% | 0.00% | 0.00% | 0.00% | 7.69% | 0.00% | 15.38% | 76.92% |
The source of the experience
eHealthmeConcepts, symbols and science items
Concepts
Symbols
Science Items
Activities and commonsteps
Activities
Overloads
Brain tumourErectile dysfunction drugs
Female sexual dysfunction drugs
Migraine treatments
Reproductive system disease
Serotonin imbalance