Observations placeholder
Zonisamide and Zonegran
Identifier
005711
Type of Spiritual Experience
Background
A description of the experience
Zonisamide - sold under the trade names Excegran and Zonegran , is an anticonvulsant in the treatment of epilepsy, approved for use as an adjunctive therapy in adults with partial-onset seizures, and generalized tonic clonic seizure. Its theoretical action is shown below
Zonisamide in the treatment of epilepsy - Holder JL, Wilfong AA. Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030 , USA.
Introduction: Epilepsy affects approximately 3 million people in the USA and up to 2% of the worldwide population. The yearly direct medical cost of epilepsy in the USA alone is estimated to be $9.5 billion. Epilepsy affects both children and adults and can significantly impair quality of life.
Zonisamide is a second-generation antiepileptic drug (AED) that has …. simpler dosing than earlier drugs.
Areas covered: The history of the development of zonisamide is reviewed in this paper. The data available demonstrating zonisamide's mechanism of action as:
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a voltage-gated sodium channel inhibitor
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a T-type calcium channel inhibitor
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an enhancer of GABA release
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and an inhibitor of glutamate release
its actual action according to eHealthme ADRs: Most common Zonisamide side effects
- Convulsion - (418 reports)
- Drug ineffective - (296 reports)
- Fever - (224 reports)
- Erythema multiforme - (180 reports)
- Fatigue - (159 reports)
- Rashes - (151 reports)
- Fall - (150 reports)
- Dizziness - (146 reports)
- Nausea and vomiting - (146 reports)
- Drowsiness - (144 reports)
On Jan, 07, 2017 3,692 people reported to have side effects when taking Zonisamide. Among them, 45 people (1.22%) have Hallucination
On Feb, 01, 2017 3,692 people reported to have side effects when taking Zonisamide. Among them, 25 people (0.68%) have Hallucination, Auditory
On Feb, 01, 2017 3,894 people reported to have side effects when taking Zonegran. Among them, 58 people (1.49%) have Hallucination
On Feb, 01, 2017 3,894 people reported to have side effects when taking Zonegran. Among them, 20 people (0.51%) have Hallucination, Auditory