Observations placeholder
The quinolones in chronic bronchitis
Identifier
020263
Type of Spiritual Experience
Background
A description of the experience
Pharm Weekbl Sci. 1986 Feb 21;8(1):53-9.
The quinolones in chronic bronchitis.
Davies BI, Maesen FP, Teengs JP, Baur C.
Abstract
Results are presented from 186 hospitalized patients treated for acute purulent exacerbations of chronic bronchitis with orally administered ciprofloxacin (80 patients), enoxacin (26 patients), ofloxacin (30 patients) or pefloxacin (50 patients). In general, good clinical results were observed in 50-70% of the patients treated, most failures being due to relapses or reinfections with Streptococcus pneumoniae or Pseudomonas aeruginosa. Studies on blood and sputum concentration suggested that gastro-intestinal absorption was not always satisfactory. Unwanted drug effects were noted with all agents studied, generally presenting as stomach pain, nausea, hallucinations, or dizziness. Most adverse drug reactions were seen with enoxacin, often but not always during concomitant treatment with theophylline.
PMID: 3960693
The source of the experience
PubMedConcepts, symbols and science items
Concepts
Symbols
Science Items
Activities and commonsteps
Activities
Overloads
AntibioticsLung disease
Pseudomonas aeruginosa infection
Streptococcus infection