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Research progress of phytoestrogens-like chemical constituents in natural medicines
Identifier
017886
Type of Spiritual Experience
Background
A description of the experience
Zhongguo Zhong Yao Za Zhi. 2014 Dec;39(23):4526-31.
[Research progress of phytoestrogens-like chemical constituents in natural medicines].
[Article in Chinese]
Yuan TT, Zhang ND, He YJ, Li M, Xu HT, Zhang QY.
Abstract
Phytoestrogens, which can bind with estrogen receptor and produce estrogen-like effects, are a kind of nonsteroidal compound in plant.
Phytoestrogens chemically include isoflavones, coumarins, lignans and other compounds.
Phytoestrogens are selective estrogen receptor modulator, and have therapeutical effects on breast cancer, prostate cancer, cardiovascular disease, menopausal symptoms, osteoporosis and other disease, however, do not produce stimulatory hyperplasia effects on uterus, mammary glands and other tissues and organs with positive estrogen receptor.
Long-term exposure or excessive use of phytoestrogens maybe affects male reproductive system and hematopoietic function of fetus.
Some questions need to be further studied, such as evaluation criteria on biological activity, adverse effects, and action mechanism of phytoestrogen. This review covers plant sources, chemical structure, pharmacological activity and safety of phytoestrogens.
It will provide a useful reference for intensive research and rational utilization the phytoestrogens.
PMID: 25911795
The source of the experience
PubMedConcepts, symbols and science items
Concepts
Symbols
Science Items
Activities and commonsteps
Activities
Overloads
Benign prostatic hyperplasiaBenign prostatic hyperplasia drugs
Cancer
Contraceptives
Estrogen imbalance
Menopause
Osteoporosis
Osteoporosis treatments
Reproductive system disease
Suppressions
Eating for healthPhytoestrogens