Pramipexole (Mirapex, Mirapexin, Sifrol) is a dopamine agonist of the non-ergoline class used for treating Parkinson's disease (PD) and restless legs syndrome (RLS)
Side effects
Common side effects of pramipexole may include:
- Headache
- Peripheral edema (Tan EK, Ondo W. Clinical characteristics of pramipexole-induced peripheral edema. Arch Neurol. 2000;57:729-732.)
- Hyperalgesia (body aches and pains)
- Nausea and vomiting
- Sedation and somnolence
- Decreased appetite and subsequent weight loss
- Orthostatic hypotension (resulting in dizziness, lightheadedness, and possibly fainting, especially when standing up)
- Insomnia
- Hallucinations (seeing, hearing, smelling, tasting or feeling things that are not there)
- Twitching, twisting, or other unusual body movements
- Unusual tiredness or weakness
Several unusual adverse effects of pramipexole (and related D3-preferring dopamine agonist medications such as ropinirole) may include compulsive gambling, punding, hypersexuality, and overeating even in patients without any prior history of these behaviours.
On Dec, 26, 2015: 9,808 people reported to have side effects when taking Mirapex. Among them, 323 people (3.29%) have Hallucination.
Time on Mirapex when people have Hallucination :
| |
< 1 month |
1 - 6 months |
6 - 12 months |
1 - 2 years |
2 - 5 years |
5 - 10 years |
10+ years |
| Hallucination |
28.05% |
15.85% |
3.66% |
7.32% |
23.17% |
21.95% |
0.00% |
Gender of people who have Hallucination when taking Mirapex :
| |
Female |
Male |
| Hallucination |
50.00% |
50.00% |
Age of people who have Hallucination when taking Mirapex :
| |
0-1 |
2-9 |
10-19 |
20-29 |
30-39 |
40-49 |
50-59 |
60+ |
| Hallucination |
0.00% |
0.00% |
0.00% |
1.42% |
1.42% |
9.48% |
10.43% |
77.25% |
Severity of Hallucination when taking Mirapex :
| |
least |
moderate |
severe |
most severe |
| Hallucination |
0.00% |
0.00% |
100.00% |
0.00% |
How people recovered from Hallucination :
| |
while on the drug |
after off the drug |
not yet |
| Hallucination |
0.00% |
50.00% |
50.00% |
On Dec, 30, 2015: 9,808 people reported to have side effects when taking Mirapex. Among them, 118 people (1.20%) have Death.
Time on Mirapex when people have Death :
| |
< 1 month |
1 - 6 months |
6 - 12 months |
1 - 2 years |
2 - 5 years |
5 - 10 years |
10+ years |
| Death |
0.00% |
30.00% |
0.00% |
0.00% |
50.00% |
20.00% |
0.00% |
Gender of people who have Death when taking Mirapex :
| |
Female |
Male |
| Death |
54.46% |
45.54% |
Age of people who have Death when taking Mirapex :
| |
0-1 |
2-9 |
10-19 |
20-29 |
30-39 |
40-49 |
50-59 |
60+ |
| Death |
0.00% |
0.00% |
0.00% |
0.00% |
1.45% |
4.35% |
14.49% |
79.71% |
