Observations placeholder
Inspra and Eplerenone
Identifier
024058
Type of Spiritual Experience
Background
A description of the experience
Eplerenone (INN) is a steroidal antimineralocorticoid of the spirolactone group that is used as an adjunct in the management of chronic heart failure. It is similar to the diuretic spironolactone, though it is much more selective for the mineralocorticoid receptor in comparison (i.e., does not possess any antiandrogen, progestogen, glucocorticoid, or estrogenic effects), and is specifically marketed for reducing cardiovascular risk in patients following myocardial infarction. Eplerenone is a potassium-sparing diuretic, meaning that it helps the body get rid of water but still keep potassium.
Eplerenone was developed by Pharmacia Corporation, which was acquired by Pfizer in 2002. It was marketed by Pfizer under the trade name Inspra. The US Food and Drug Administration (FDA) approved the drug for sale in the United States in 2002. Eplerenone is currently approved for sale in the US, EU, Netherlands and Japan. Relative to dosage, eplerenone costs an estimated $2.93 per day when treating congestive heart failure and $5.86 per day when treating hypertension.
Most common Inspra side effects from eHealthme
- Breathing difficulty - (143 reports)
- Hypotension - (110 reports)
- Renal failure acute - (104 reports)
- Weakness - (101 reports)
- Dizziness - (101 reports)
- Nausea - (94 reports)
- Acute kidney failure - (88 reports)
- Fatigue - (87 reports)
- Cardiac failure congestive - (82 reports)
- Cardiac failure - (76 reports)
Most common Eplerenone side effects
- Cardiac failure - (176 reports)
- Hyperkalemia - (128 reports)
- Renal failure acute - (119 reports)
- Hypotension - (116 reports)
- Weakness - (96 reports)
- Acute kidney failure - (95 reports)
- Breathing difficulty - (92 reports)
- Dizziness - (92 reports)
- Fatigue - (89 reports)
- Renal impairment - (86 reports)
On Jan, 26, 2017 1,721 people reported to have side effects when taking Inspra. Among them, 20 people (1.16%) have Hallucination
On Jan, 28, 2017 2,045 people reported to have side effects when taking Eplerenone. Among them, 11 people (0.54%) have Hallucination
On Feb, 07, 2017 2,045 people reported to have side effects when taking Eplerenone. Among them, 1 person (0.05%) has Hallucination, Auditory