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In vitro angiotensin converting enzyme inhibiting activity of Salsola oppositifolia Desf., Salsola soda L. and Salsola tragus L.
Identifier
021292
Type of Spiritual Experience
Background
A description of the experience
Nat Prod Res. 2007 Jul 20;21(9):846-51. In vitro angiotensin converting enzyme inhibiting activity of Salsola oppositifolia Desf., Salsola soda L. and Salsola tragus L. Loizzo MR1, Tundis R, Statti GA, Passalacqua NG, Peruzzi L, Menichini F. 1Department of Pharmaceutical Sciences, University of Calabria, Arcavacata di Rende, CS, Italy. mr.loizzo@unical.it
In order to support scientifically the traditional use of Salsola species in the treatment of hypertension, this study was designed to evaluate the hypotensive properties of Salsola oppositifolia, S. soda and S. tragus. In vitro bio-assay based on the measured enzymatic cleavage of the chromophore-fluorophore-labelled substrate dansyltriglycine into dansylglycine and diglycine by angiotensin converting enzyme (ACE) was performed. EtOAc extracts of S. oppositifolia and S. soda exhibited an interesting activity with an IC(50) of 181.04 and 284.27 microg mL(-1), respectively.
PMID: 17763103