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Gripp Heel herpes and flu
Identifier
005323
Type of Spiritual Experience
Background
A description of the experience
In vitro evaluation of the antiviral effects of the homeopathic preparation Gripp-Heel on selected respiratory viruses - Glatthaar-Saalmüller B; Clinical Immunology, University of Veterinary Medicine Vienna, A-1210 Vienna, Austria.
Gripp-Heel is a homeopathic preparation frequently used in the treatment of respiratory viral infections such as various types of influenza and the common cold.
The antiviral activity of Gripp-Heel was studied in vitro on human pathogenic enveloped and nonenveloped RNA and DNA viruses. Before the antiviral assays, in vitro cytotoxicity of Gripp-Heel was determined with cells used for the infection experiments (HeLa, HEp-2, MDCK, BGM) as well as with mitogen-stimulated peripheral blood mononuclear leukocytes.
A concentration of 0.5 of the commercially available product slightly reduced cell viability and proliferative capacity, and experiments on antiviral activity were determined starting with a dilution of 0.2 of the commercially available product.
The antiviral activity was determined against a broad panel of enveloped and nonenveloped DNA and RNA viruses with plaque reduction assay, cytopathogenic assays, virus titrations, analysis of the viral proteins in virus-specific enzyme immunoassays, and haemagglutination tests. Control substances were acyclovir (10 microg/mL), ribavirin (6 microg/mL), and amantadine hydrochloride (5 microg/mL), depending on the virus type. Gripp-Heel demonstrated dose-dependent in vitro activity (significant reductions of infectivity by 20% to 40%) against
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Human herpesvirus 1
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Human adenovirus C serotype 5
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Influenza A virus
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Human respiratory syncytial virus
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Human parainfluenza virus 3
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Human rhinovirus B serotype 14
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and Human coxsackievirus serotype A9
The mechanisms of this antiviral activity are still unclear, but type I interferon induction might be a possible explanation. Further research on this homeopathic preparation seems warranted.
The source of the experience
PubMedConcepts, symbols and science items
Concepts
Symbols
Science Items
HomeopathyActivities and commonsteps
Activities
Overloads
Bacterial infectionCoxsackievirus infection
Herpes simplex
Influenza
Viral infection