Observations placeholder
Garlic and atherosclerosis
Identifier
006173
Type of Spiritual Experience
Background
A description of the experience
Nutrition. 1997 Jul-Aug;13(7-8):656-63. Effects of garlic on atherosclerosis. Orekhov AN, Grünwald J. Institute of Experimental Cardiology, Cardiology Research Center of the Russian Academy of Medical Sciences, Moscow, Russia.
This review discusses the use of garlic and garlic preparations as agents for prevention and treatment of atherosclerosis and atherosclerosis-related diseases. Garlic indirectly effects atherosclerosis by reduction of hyperlipidemia, hypertension, and probably diabetes mellitus and prevents thrombus formation. In addition, in animal models, garlic causes direct antiatherogenic (preventive) and antiatherosclerotic (causing regression) effects at the level of artery wall. Garlic's direct effect on atherosclerosis may be explained by its capacity to reduce lipid content in arterial cells and to prevent intracellular lipid accumulation. This effect, in turn, is accompanied by other atherosclerotic manifestations, i.e., stimulation of cell proliferation and extracellular matrix synthesis. Clinical trials are currently being carried out to reveal the possible effect of garlic therapy on human atherosclerosis. Positive results of these trials may open a new era in the use of garlic for prevention and treatment of many atherosclerosis-related diseases.
PMID: 9263259
The source of the experience
PubMedConcepts, symbols and science items
Concepts
Symbols
Science Items
Activities and commonsteps
Activities
Overloads
AtherosclerosisEndothelial dysfunction
Hypertension