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Fish oil, evening primrose oil, linoleic acid and psoriasis
Identifier
012002
Type of Spiritual Experience
Background
A description of the experience
Allerg Immunol (Paris). 1990 Jun;22(6):225-31. [Essential fatty acids and the skin]. [Article in French] Berbis P1, Hesse S, Privat Y. Clinique Dermatologique, Hôtel Dieu, Marseille.
Metabolism of the essential fatty acids (AGE) in an organism leads to synthesis of eicosanoids, which have various biological properties.
Linoleic acid plays an important part in maintenance of epidermal integrity by intervening in the cohesion of the stratum corneum and in prevention of transepidermal water loss.
Metabolites of arachidonic acid (mostly those obtained by the lipoxygenase pathway) are important agents in causing many inflammatory skin reactions concurrent with development of skin diseases such as psoriasis and atopic dermatitis.
Pharmacological and dietetic control of the metabolism of arachidonic acid is a new and interesting therapeutic concept in the care of skin diseases.
Also, fish oil, which is rich in linoleic acid and poor in arachidonic acid, seems to be useful in basal treatment of psoriasis. The value of evening primrose oil, which is rich in gamma-linoleic acid, in the treatment of atopic dermatitis is discussed.
PMID: 2143069