Observations placeholder
Coffee and obesity
Identifier
005619
Type of Spiritual Experience
Background
A description of the experience
Semin Thromb Hemost. 2012 Mar;38(2):164-77. doi: 10.1055/s-0032-1301414. Epub 2012 Feb 18.
Coffee intake and cardiovascular disease: virtue does not take center stage. Montagnana M, Favaloro EJ, Lippi G. Sezione di Biochimica Clinica, Dipartimento di Scienze della Vita e della Riproduzione, Università di Verona, Verona, Italy. martina.montagnana@med.lu.se
Coffee is one of the most popular and heavily consumed beverages worldwide, despite the many different methods of preparation and presentation.
The results of several epidemiological studies are suggestive for the existence of a U-shaped relationship between coffee consumption and both cardiovascular events and mortality, whereby a lower risk seems associated with low (i.e., less than one cup per day) or high (i.e., more than or equal to four cups per day) coffee intake, whereas a higher risk is reported for intermediate consumption (i.e., two to four cups per day).
Most benefits are evident in individuals with a rapid caffeine metabolizer genotype and a low baseline cardiovascular risk.
Benefits have also been differentially associated with consumption of decaffeinated coffee, filtered coffee, coffee consumption during lunchtime or dinner, and when coffee is produced in the Italian style (i.e., by espresso or moka).
The leading favorable effects have been attributed to various compounds present in coffee. Thus, chlorogenic acids would be effective in decreasing blood pressure, systemic inflammation, risk of type 2 diabetes, and platelet aggregation, whereas caffeine intake has instead been associated with decreased body weight, as well as with increased flow-mediated dilatation and fibrinolysis.
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
PMID: 22422331
The source of the experience
PubMedConcepts, symbols and science items
Concepts
Symbols
Science Items
Activities and commonsteps
Activities
Overloads
DiabetesDiabetes treatments
Endothelial dysfunction
Heart failure and coronary heart disease
Hypertension
Obesity