Observations placeholder
Chocolate, Gingko biloba, bilberries and glaucoma
Identifier
005654
Type of Spiritual Experience
Background
IOP = Intraocular pressure, the fluid pressure inside the eye
A description of the experience
Klin Monbl Augenheilkd. 2013 Feb;230(2):114-9. doi: 10.1055/s-0032-1327825. Epub 2013 Feb 21. [Value of non-IOP lowering therapy for glaucoma]. [Article in German] Cybulska-Heinrich A, Mozaffarieh M, Flammer J. Department of Ophthalmology, University of Basel, Switzerland.
It is well established that an IOP reduction improves, on average, the prognosis of all types of glaucoma.
It is also known, however, that even an ideal IOP does not stop progression in all patients. The insight into the pathogenesis of glaucomatous damage leads to new therapeutic approaches.
Whilst most of these new avenues of treatment are still in the experimental phase, others, such as magnesium, Ginkgo, and salt are already used by some physicians.
..... A number of other food ingredients such as polyphenolic flavonoids occurring in tea, coffee, dark chocolate or red wine and anthocyanosides found in bilberries have potential antioxidative effects.
The oxidative stress at the level of the mitochondria can be reduced by Ginkgo biloba.
Experimentally, glaucomatous optic neuropathy can be prevented by inhibition of astrocyte activation, either by blockage of epidermal growth factor receptor or by counteracting endothelin. Glaucomatous optic neuropathy can also be prevented by nitric oxide-2 synthase inhibition. Inhibition of matrix metalloproteinase-9 inhibits apoptosis of retinal ganglion cells and tissue remodelling. Up-regulation of heat shock proteins protects the retinal ganglion cells and the optic nerve head.
Georg Thieme Verlag KG Stuttgart · New York.
PMID: 23430676
The source of the experience
PubMedConcepts, symbols and science items
Concepts
Symbols
Science Items
Activities and commonsteps
Activities
Overloads
Eye diseaseEye disease treatments - glaucoma
Eye disease treatments - macular degeneration
Magnesium imbalance
Suppressions
AnthocyanidinAnthocyanin
Bilberries
Blindness, macular degeneration and other sight impairment
Chocolate
Coffee
Ginkgo biloba
Polyphenols
Red wine
Tea