Observations placeholder
Anaphylaxis to drugs
Identifier
025498
Type of Spiritual Experience
Background
A description of the experience
Immunol Allergy Clin North Am. 2015 May;35(2):303-19. doi: 10.1016/j.iac.2015.01.008. Epub 2015 Mar 3.
Anaphylaxis to drugs.
Kuruvilla M1, Khan DA2.
Atlanta ENT, 5555 Peachtree Dunwoody Rd, Suite 125, Atlanta, GA-30342, USA.
2 Division of Allergy & Immunology, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-8859, USA. Electronic address: dave.khan@utsouthwestern.edu.
Abstract
Drug-induced anaphylaxis is a common cause of anaphylaxis and a leading cause of fatal anaphylaxis. Antibiotics, radiocontrast, and nonsteroidal anti-inflammatory drugs are commonly implicated drugs.
Vocal cord dysfunction can mimic anaphylaxis and is often overlooked. β-Lactams are a common cause of anaphylaxis; however, skin testing and drug challenge can usually determine tolerability of other classes of β-lactams.
Nonionic contrast agents cause anaphylaxis less frequently than ionic contrast, and immunoglobulin E-mediated mechanisms may have a role in some of these reactions. Skin testing with radiocontrast may have a role in evaluating patients with anaphylaxis to nonionic contrast.
Copyright © 2015 Elsevier Inc. All rights reserved.
KEYWORDS:
Anaphylaxis; Cephalosporin; Drug; NSAID; Penicillin; Proton pump inhibitor; Radiocontrast; Vocal cord dysfunction
PMID:
25841553
The source of the experience
PubMedConcepts, symbols and science items
Concepts
Symbols
Science Items
Activities and commonsteps
Activities
Overloads
AnaphylaxisAntibiotics
MRI Contrast agents
Pain killers and NSAIDS
Proton Pump Inhibitors PPIs