Observations placeholder
Acute psychosis induced by isotretinoin
Identifier
017642
Type of Spiritual Experience
Background
A description of the experience
Indian J Psychiatry. 2014 Jul;56(3):295-7. doi: 10.4103/0019-5545.140652.
Acute psychosis induced by isotretinoin.
Rajagopal S1.
- 1Girishwari Hospital, Chennai, Tamil Nadu, India.
Abstract
Isotretinoin is used for the treatment of severe acne. Psychiatric side-effects, particularly depression, have been well-documented.
This dramatic case report is about a young male patient who developed acute psychosis within a few days of starting isotretinoin. Due to his persecutory delusions, the patient, who was an Indian engineer working in Germany, decided to immediately return to India fearing for his life in Germany.
Careful history taking established the cause of the psychosis. Isotretinoin was stopped; patient showed rapid improvement, within a week, on a low dose of risperidone. Risperidone was continued as a precaution for 3 months. After a further 8 months, the patient remains well without any psychotropic medication.
KEYWORDS:
Acne; depression; isotretinoin; psychosis
PMID:
25316943